04
Mesenchymal Stem Cell
Mesenchymal Stem Cell (MSCs) are multipotent stem cell found in various tissues, including:
- Bone marrow
- Adipose tissue
- Umbilical cord
- Placenta
MSCs have the ability to self-renew and differentiate into multiple cell types, such as:
- Osteoblasts (bone cells)
- Chondrocytes (cartilage cells)
- Adipocytes (fat cells)
4.1
Key Functions of MSCs
- Promote tissue repair and regeneration
- Reduce inflammation and regulate immune responses (immunomodulation)
- Secrete bioactive factors that enhance cellular recovery
4.2
Sources of MSCs
| Source | Abbreviation | Key Characteristics |
|---|---|---|
| Bone marrow | BM-MSCs | Traditional source, extensively studied |
| Adipose tissue | AD-MSCs / ADSCs | Easy to harvest, high cell yield |
| Umbilical cord | UC-MSCs | High proliferation, low immunogenicity, widely used in therapy |
| Wharton’s jelly | WJ-MSCs | Strong proliferation and immunomodulation |
| Placenta | P-MSCs | Non-invasive collection post-delivery |
| Amniotic membrane | AM-MSCs | Strong anti-inflammatory properties |